EEPD1

Across TCGA cell cohorts, EEPD1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible EEPD1-associated genes across cancer lineages are HHLA1, USP29, and CCDC172. Each is linked with EEPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEPD1-to-partner and partner-to-EEPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HHLA1 grouped by EEPD1-low versus EEPD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEPD1→partner) and Y-score (partner→EEPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HHLA1 →	+0.009	+3.551	<.001	.009	3	2
LARGE_INTESTINE	USP29 →	+0.014	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCDC172 →	+0.004	+4.415	<.001	.007	3	1
BLOOD_Leukemia	GZMK →	+0.448	+4.037	.004	.004	3	1
BLOOD_Leukemia	C2orf73 →	+0.052	+4.450	<.001	.001	3	1
BLOOD_Leukemia	CCT8L2 →	+0.009	+3.874	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

HHLA1 by EEPD1 expression — BLOOD_Leukemia

Explore this box plot interactively →