EEFSEC

Across TCGA patient cohorts, EEFSEC protein abundance is significantly associated with the RNA expression of many other genes, with 8,667 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EEFSEC-associated genes across cancer lineages are UBA5, ARMC8, and UMPS. Each is linked with EEFSEC in more than 5 cancer types. Because this analysis shows association rather than direction, both EEFSEC-to-partner and partner-to-EEFSEC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EEFSEC versus UBA5 in CCRCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEFSEC→partner) and Y-score (partner→EEFSEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	UBA5 →	+0.815	+0.296	<.001	<.001	3	6
HNSC	ARMC8 →	+0.376	+0.236	.007	<.001	2	6
LSCC	UMPS →	+0.840	+0.273	<.001	<.001	3	5
LSCC	NEK11 →	+0.777	+0.257	<.001	<.001	3	5
HNSC	SEC22A →	+0.393	+0.177	<.001	<.001	3	5
HNSC	POGLUT1 →	+0.563	+0.230	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,667 associations by consensus.

EEFSEC vs UBA5 — CCRCC

Explore this scatter interactively →