EEFSEC

Across TCGA cell cohorts, EEFSEC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,546 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EEFSEC-associated GO terms across cancer lineages are U2-type prespliceosome assembly, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with EEFSEC in more than 13 cancer types. Because this analysis shows association rather than direction, both EEFSEC-to-partner and partner-to-EEFSEC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U2-type prespliceosome assembly grouped by EEFSEC-low versus EEFSEC-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EEFSEC→partner) and Y-score (partner→EEFSEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	U2-type prespliceosome assembly →	+0.101	+0.813	.009	<.001	2	14
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.159	+0.745	<.001	<.001	3	13
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.159	+0.745	<.001	<.001	3	13
OESOPHAGUS	Regulation of protein localization to chromatin →	+0.117	+0.920	.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA damage checkpoint signaling →	+0.093	+0.934	<.001	<.001	3	13
LUNG_NSCLC_LUSC	mRNA 3'-splice site recognition →	+0.134	+0.746	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,546 associations by consensus.

U2-type prespliceosome assembly by EEFSEC expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →