EEF2KMT

Across TCGA patient cohorts, EEF2KMT mutation is significantly associated with the RNA expression of many other genes, with 2,483 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF2KMT-associated genes across cancer lineages are H3Y1, RNU6-1318P, and LINC00399. Each is linked with EEF2KMT in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF2KMT-to-partner and partner-to-EEF2KMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H3Y1 grouped by EEF2KMT-low versus EEF2KMT-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF2KMT→partner) and Y-score (partner→EEF2KMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H3Y1 →	+0.706	+2.103	<.001	<.001	3	2
UCEC	RNU6-1318P →	+0.236	+2.358	<.001	.004	3	2
SKCM	LINC00399 →	+0.104	+3.458	.001	.003	3	2
UCEC	PSG9 →	+0.106	+1.585	<.001	.006	3	2
UCEC	RNU6-1245P →	+0.228	+2.081	<.001	.009	3	2
UCEC	MTND5P35 →	+0.057	+2.236	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,483 associations by consensus.

H3Y1 by EEF2KMT expression — UCEC

Explore this box plot interactively →