EEF2KMT

Across TCGA pan-cancer cohorts, EEF2KMT RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated EEF2KMT data layer compared with 3 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher EEF2KMT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EEF2KMT expression acts as an unfavorable survival marker, although some lineages such as OV and KIRC show a favorable association.

ACC, BLCA, and MESO are the cancer types where EEF2KMT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.769	0.967	<.001	76	view →
BLCA	DFS	Median	All	0.483	0.691	.002	69	view →
MESO	OS	Tertile	II,III,IV	0.445	0.683	.004	59	view →
SCLC	DFS	Median	II,III,IV	0.208	0.640	<.001	44	view →
LIHC	OS	Quartile	All	0.505	0.773	<.001	40	view →
OV	DFS	Median	IV	0.611	0.312	<.001	34	view →
PAAD	DFS	Median	All	0.405	0.558	.005	26	view →
KIRC	DFS	Median	III,IV	0.601	0.274	.006	18	view →
BRCA	OS	Tertile	IV	0.698	0.178	.011	18	view →
KIRP	DFS	Tertile	IV	0.456	0.700	.017	18	view →
READ	DFS	Tertile	All	0.800	0.418	.010	16	view →
SKCM	OS	Tertile	All	0.302	0.406	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

EEF2KMT–ACC (OS)

Open the ACC breakdown →