EEF1E1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EEF1E1 mutation is significantly associated with the RNA expression of many other genes, with 179 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1E1-associated genes across cancer lineages are RN7SL769P, TRAJ21, and AKIRIN1P2. Each is linked with EEF1E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1E1-to-partner and partner-to-EEF1E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL769P grouped by EEF1E1-low versus EEF1E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1E1→partner) and Y-score (partner→EEF1E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL769P →+0.318+2.432.005.00932
UCECTRAJ21 →+0.897+3.936<.001<.00132
UCECAKIRIN1P2 →+0.231+2.664.007.00532
UCECRPL7AP23 →+0.087+3.105<.001.00132
UCECMAGEB10 →+0.109+3.326.003<.00132
COADRNU6-1329P →+0.363+5.547.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 179 associations by consensus.

RN7SL769P by EEF1E1 expression — UCEC

Box plot of RN7SL769P in EEF1E1-low vs EEF1E1-high samples in UCEC.

Explore this box plot interactively →

Exploration