EEF1E1-BLOC1S5

Across TCGA patient cohorts, EEF1E1-BLOC1S5 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1E1-BLOC1S5-associated genes across cancer lineages are MIR4507, BNIP3P4, and MIR4727. Each is linked with EEF1E1-BLOC1S5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1E1-BLOC1S5-to-partner and partner-to-EEF1E1-BLOC1S5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4507 grouped by EEF1E1-BLOC1S5-low versus EEF1E1-BLOC1S5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1E1-BLOC1S5→partner) and Y-score (partner→EEF1E1-BLOC1S5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4507 →	+0.613	+5.420	<.001	.005	3	1
UCEC	BNIP3P4 →	+0.287	+5.484	<.001	.005	3	1
UCEC	MIR4727 →	+0.721	+5.551	<.001	.004	3	1
UCEC	MIR147A →	+0.817	+6.582	<.001	.001	3	1
UCEC	MIR33A →	+0.610	+5.186	.001	.007	3	1
UCEC	IGHD1-26 →	+1.890	+5.484	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MIR4507 by EEF1E1-BLOC1S5 expression — UCEC

Explore this box plot interactively →