EEF1D

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EEF1D mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EEF1D-associated genes across cancer lineages are HTR3D, RBMY1D, and USP17L20. Each is linked with EEF1D in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1D-to-partner and partner-to-EEF1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR3D grouped by EEF1D-low versus EEF1D-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1D→partner) and Y-score (partner→EEF1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaHTR3D →+0.019+5.539<.001.00331
BLOOD_LeukemiaRBMY1D →+0.180+5.539<.001.00331
BLOOD_LeukemiaUSP17L20 →+0.006+5.539<.001.00331
BLOOD_LeukemiaUSP17L18 →+0.006+5.539<.001.00331
BLOOD_LeukemiaKRTAP7-1 →+0.105+5.539<.001.00331
LARGE_INTESTINETAFA1 →+0.274+3.688<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

HTR3D by EEF1D expression — BLOOD_Leukemia

Box plot of HTR3D in EEF1D-low vs EEF1D-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration