EEF1B2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EEF1B2 mutation is significantly associated with the RNA expression of many other genes, with 862 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1B2-associated genes across cancer lineages are FAM197Y4, SNORD3C, and MIR6792. Each is linked with EEF1B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF1B2-to-partner and partner-to-EEF1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM197Y4 grouped by EEF1B2-low versus EEF1B2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1B2→partner) and Y-score (partner→EEF1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMFAM197Y4 →+0.099+7.816<.001.00833
UCECSNORD3C →+0.017+3.928<.001.00732
BRCAMIR6792 →+0.628+4.971<.001.00531
UCECHMGB1P50 →+0.154+2.413.002.00131
UCECPOM121C →+0.494+3.609<.001.00131
UCECZNHIT3 →+0.467+2.724.004.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 862 associations by consensus.

FAM197Y4 by EEF1B2 expression — SKCM

Box plot of FAM197Y4 in EEF1B2-low vs EEF1B2-high samples in SKCM.

Explore this box plot interactively →

Exploration