EEF1AKNMT

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EEF1AKNMT mutation is significantly associated with the RNA expression of many other genes, with 1,564 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1AKNMT-associated genes across cancer lineages are RPS27AP15, SHPK, and EXOSC9. Each is linked with EEF1AKNMT in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF1AKNMT-to-partner and partner-to-EEF1AKNMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS27AP15 grouped by EEF1AKNMT-low versus EEF1AKNMT-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1AKNMT→partner) and Y-score (partner→EEF1AKNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCRPS27AP15 →+0.056+3.350.001.00833
UCECSHPK →+0.408+2.238.002.00633
COADEXOSC9 →+0.558+3.222.001.00833
UCECZFYVE19 →+0.382+2.721.004.00333
UCECRIMKLA →+0.885+2.617<.001<.00133
UCECKRT18P55 →+0.215+2.162<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,564 associations by consensus.

RPS27AP15 by EEF1AKNMT expression — LIHC

Box plot of RPS27AP15 in EEF1AKNMT-low vs EEF1AKNMT-high samples in LIHC.

Explore this box plot interactively →

Exploration