EEF1AKMT3

Across TCGA patient cohorts, EEF1AKMT3 mutation is significantly associated with the RNA expression of many other genes, with 463 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1AKMT3-associated genes across cancer lineages are RNU7-95P, WHAMM, and ATXN7. Each is linked with EEF1AKMT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1AKMT3-to-partner and partner-to-EEF1AKMT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-95P grouped by EEF1AKMT3-low versus EEF1AKMT3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1AKMT3→partner) and Y-score (partner→EEF1AKMT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU7-95P →	+0.627	+7.640	<.001	.009	3	2
UCEC	WHAMM →	+0.893	+3.354	<.001	.005	3	1
UCEC	ATXN7 →	+0.587	+3.332	.003	.005	3	1
UCEC	C9orf64 →	+0.884	+3.364	.001	.005	3	1
UCEC	MARCHF8 →	+0.631	+3.343	.003	.005	3	1
UCEC	ZNF641 →	+0.505	+3.332	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 463 associations by consensus.

RNU7-95P by EEF1AKMT3 expression — BLCA

Explore this box plot interactively →