EDRF1-AS1

Across TCGA pan-cancer cohorts, EDRF1-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated EDRF1-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EDRF1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated EDRF1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, BRCA, and KICH are the cancer types where EDRF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.419	0.250	<.001	124	view →
BRCA	DFS	Median	III,IV	0.605	0.294	.001	40	view →
KICH	DFS	Quartile	III,IV	0.194	1.000	.004	38	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	35	view →
ACC	OS	Tertile	All	0.569	0.893	.002	32	view →
READ	OS	Tertile	All	1.000	0.868	.003	28	view →
UCS	DFS	Tertile	IV	0.932	0.361	.024	24	view →
DLBC	DFS	Median	All	0.617	0.917	.008	18	view →
KIRC	DFS	Median	All	0.490	0.672	.019	16	view →
SKCM	OS	Quartile	All	0.438	0.230	.006	15	view →
BLCA	OS	Tertile	All	0.805	0.659	.008	13	view →
KIRP	DFS	Tertile	All	1.000	0.823	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

EDRF1-AS1–HNSC (DFS)

Open the HNSC breakdown →