EDNRB

Across TCGA pan-cancer cohorts, EDNRB mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EDNRB data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher EDNRB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EDNRB expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

GBM, CCRCC, and LUAD are the cancer types where EDNRB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.620	0.321	.008	6	view →
CCRCC	DFS	Median	All	0.639	0.963	.016	5	view →
LUAD	OS	Quartile	II,III,IV	0.847	0.522	.042	2	view →
LSCC	OS	Quartile	II,III,IV	0.919	0.521	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EDNRB–GBM (DFS)

Open the GBM breakdown →