EDNRB

Across TCGA patient cohorts, EDNRB RNA expression is significantly associated with the protein abundance of many other proteins, with 23,350 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EDNRB-associated proteins across cancer lineages are SYNM, PLVAP, and PRKG1. Each is linked with EDNRB in more than 7 cancer types. Because this analysis shows association rather than direction, both EDNRB-to-partner and partner-to-EDNRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDNRB versus SYNM in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDNRB→partner) and Y-score (partner→EDNRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SYNM →	+0.834	+0.544	<.001	<.001	3	8
CCRCC	PLVAP →	+0.855	+1.614	<.001	<.001	3	8
UCEC	PRKG1 →	+0.774	+0.701	<.001	.001	3	8
OV	SEPTIN4 →	+0.747	+1.175	<.001	<.001	3	8
UCEC	FERMT2 →	+0.583	+0.669	<.001	<.001	3	8
HNSC	FHL1 →	+1.780	+0.965	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,350 associations by consensus.

EDNRB vs SYNM — HNSC

Explore this scatter interactively →