EDNRB

Across TCGA patient cohorts, EDNRB protein abundance is significantly associated with the RNA expression of many other genes, with 6,393 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EDNRB-associated genes across cancer lineages are SGCG, UST, and NEK3. Each is linked with EDNRB in more than 2 cancer types. Because this analysis shows association rather than direction, both EDNRB-to-partner and partner-to-EDNRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDNRB versus SGCG in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDNRB→partner) and Y-score (partner→EDNRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SGCG →	+0.483	+0.534	<.001	<.001	3	2
GBM	UST →	+0.754	+0.528	<.001	.009	3	2
GBM	NEK3 →	+0.445	+0.493	.009	.005	3	2
LUAD	VPS33A →	-0.209	-0.269	.003	.001	3	2
GBM	SLC14A1 →	+1.762	+0.727	<.001	<.001	3	2
GBM	GPM6A →	+0.834	+0.725	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,393 associations by consensus.

EDNRB vs SGCG — GBM

Explore this scatter interactively →