EDNRB

Across TCGA cell cohorts, EDNRB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,065 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EDNRB-associated GO terms across cancer lineages are Regulation of intracellular transport, Aldosterone metabolic process, and Regulation of penile erection. Each is linked with EDNRB in more than 7 cancer types. Because this analysis shows association rather than direction, both EDNRB-to-partner and partner-to-EDNRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport grouped by EDNRB-low versus EDNRB-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDNRB→partner) and Y-score (partner→EDNRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of intracellular transport →	+0.046	+0.333	.001	.007	3	8
BLOOD_Myeloma	Aldosterone metabolic process →	+2.270	+6.066	<.001	<.001	3	7
BLOOD_Myeloma	Regulation of penile erection →	+1.894	+5.826	<.001	<.001	3	7
BLOOD_Myeloma	Positive regulation of penile erection →	+1.894	+5.826	<.001	<.001	3	7
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.127	+0.151	.008	.007	3	7
BLOOD_Myeloma	Chordate pharynx development →	+2.007	+5.560	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,065 associations by consensus.

Regulation of intracellular transport by EDNRB expression — LIVER

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