EDNRA

Across TCGA pan-cancer cohorts, EDNRA mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EDNRA data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher EDNRA mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EDNRA expression acts as an unfavorable survival marker.

GBM, LSCC, and LUAD are the cancer types where EDNRA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.295	0.452	.018	11	view →
LSCC	DFS	Median	All	0.533	1.000	.012	6	view →
LUAD	DFS	Median	II,III,IV	0.196	1.000	.038	6	view →
UCEC	DFS	Quartile	All	0.787	1.000	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EDNRA–GBM (OS)

Open the GBM breakdown →