EDNRA

Across TCGA cell cohorts, EDNRA mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EDNRA-associated genes across cancer lineages are OR10W1, CD300H, and GYS2. Each is linked with EDNRA in more than 1 cancer types. Because this analysis shows association rather than direction, both EDNRA-to-partner and partner-to-EDNRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by EDNRA-low versus EDNRA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDNRA→partner) and Y-score (partner→EDNRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	1
SKIN	GYS2 →	+0.018	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10W1 by EDNRA expression — LARGE_INTESTINE

Explore this box plot interactively →