EDN1

Across TCGA patient cohorts, EDN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,879 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EDN1-associated proteins across cancer lineages are PPM1F, LAMB2, and SRP72. Each is linked with EDN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EDN1-to-partner and partner-to-EDN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDN1 versus PPM1F in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDN1→partner) and Y-score (partner→EDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPM1F →	+0.236	+1.247	<.001	<.001	3	5
COAD	LAMB2 →	+0.535	+1.065	.002	.001	3	5
BRCA	SRP72 →	-0.181	-1.134	<.001	<.001	3	5
OV	CAVIN1 →	+0.545	+1.149	.005	.004	3	4
CCRCC	EEF2 →	-0.221	-1.756	<.001	<.001	3	4
LSCC	GOLPH3L →	-0.325	-0.761	.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,879 associations by consensus.

EDN1 vs PPM1F — LSCC

Explore this scatter interactively →