EDN1

Across TCGA patient cohorts, EDN1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,096 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EDN1-associated genes across cancer lineages are CFHR3, AKR1A1, and TAS2R9. Each is linked with EDN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EDN1-to-partner and partner-to-EDN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDN1 versus CFHR3 in LUAD, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDN1→partner) and Y-score (partner→EDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CFHR3 →	+1.117	+0.800	.002	.002	3	1
LUAD	AKR1A1 →	+0.539	+0.922	.002	.008	3	1
LUAD	TAS2R9 →	+0.564	+1.202	<.001	.003	3	1
LUAD	OARD1 →	+0.709	+0.808	<.001	.002	3	1
LUAD	MED20 →	+0.548	+0.728	.003	.008	3	1
LUAD	SLC35B3 →	+0.922	+1.237	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,096 associations by consensus.

EDN1 vs CFHR3 — LUAD

Explore this scatter interactively →