EDN1

Across TCGA cell cohorts, EDN1 RNA expression is significantly associated with the RNA expression of many other genes, with 7,530 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EDN1-associated genes across cancer lineages are THBS1, NEDD9, and CCN1. Each is linked with EDN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both EDN1-to-partner and partner-to-EDN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDN1 versus THBS1 in BONE, with a Pearson correlation of 0.67.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDN1→partner) and Y-score (partner→EDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	THBS1 →	+5.461	+2.043	<.001	<.001	3	9
BONE	NEDD9 →	+2.516	+3.049	<.001	<.001	3	8
BONE	CCN1 →	+3.524	+2.017	<.001	<.001	3	8
LIVER	GADD45B →	+2.286	+2.478	.001	<.001	2	9
LIVER	FSTL3 →	+2.991	+2.512	<.001	<.001	2	9
BONE	AJUBA →	+2.060	+2.933	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,530 associations by consensus.

EDN1 vs THBS1 — BONE

Explore this scatter interactively →