EDN1

Across TCGA cell cohorts, EDN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,161 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EDN1-associated GO terms across cancer lineages are Maternal process involved in parturition, Glomerular endothelium development, and Artery smooth muscle contraction. Each is linked with EDN1 in more than 17 cancer types. Because this analysis shows association rather than direction, both EDN1-to-partner and partner-to-EDN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maternal process involved in parturition grouped by EDN1-low versus EDN1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDN1→partner) and Y-score (partner→EDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Maternal process involved in parturition →	+1.407	+3.447	<.001	<.001	3	18
KIDNEY	Glomerular endothelium development →	+2.006	+3.507	<.001	<.001	3	16
OESOPHAGUS	Artery smooth muscle contraction →	+1.616	+2.761	<.001	<.001	3	16
LIVER	Positive regulation of sarcomere organization →	+1.735	+3.234	<.001	<.001	3	16
OESOPHAGUS	Vein smooth muscle contraction →	+1.707	+2.803	<.001	<.001	3	15
KIDNEY	Positive regulation of odontogenesis →	+1.723	+4.027	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,161 associations by consensus.

Maternal process involved in parturition by EDN1 expression — KIDNEY

Explore this box plot interactively →