EDEM3

Across TCGA patient cohorts, EDEM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,944 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EDEM3-associated proteins across cancer lineages are RO60, ACBD3, and RNPEP. Each is linked with EDEM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both EDEM3-to-partner and partner-to-EDEM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDEM3 versus RO60 in HNSC, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDEM3→partner) and Y-score (partner→EDEM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RO60 →	+0.267	+0.355	<.001	.004	3	5
UCEC	ACBD3 →	+0.344	+0.649	<.001	<.001	3	5
BRCA	RNPEP →	+0.371	+0.829	<.001	<.001	3	5
UCEC	BPNT1 →	+0.342	+0.370	<.001	<.001	3	5
BRCA	BROX →	+0.436	+0.768	<.001	<.001	3	5
UCEC	GGPS1 →	+0.454	+0.443	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,944 associations by consensus.

EDEM3 vs RO60 — HNSC

Explore this scatter interactively →