EDEM1

Across TCGA patient cohorts, EDEM1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,856 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EDEM1-associated genes across cancer lineages are EFHD1, CYP20A1, and CPXM2. Each is linked with EDEM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EDEM1-to-partner and partner-to-EDEM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDEM1 versus EFHD1 in CCRCC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EDEM1→partner) and Y-score (partner→EDEM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EFHD1 →	-1.461	-1.165	.007	.005	3	2
CCRCC	CYP20A1 →	-0.622	-1.155	.003	.003	3	2
CCRCC	CPXM2 →	-1.074	-0.694	.002	.003	3	2
CCRCC	NIPSNAP3A →	-0.538	-0.703	<.001	.003	3	2
CCRCC	SPAG8 →	-0.504	-0.704	.002	.003	3	2
CCRCC	RMC1 →	-0.432	-0.699	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,856 associations by consensus.

EDEM1 vs EFHD1 — CCRCC

Explore this scatter interactively →