EDDM3A

Across TCGA patient cohorts, EDDM3A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,799 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EDDM3A-associated GO terms across cancer lineages are Respiratory system development, Positive regulation of immune effector process, and B cell activation. Each is linked with EDDM3A in more than 10 cancer types. Because this analysis shows association rather than direction, both EDDM3A-to-partner and partner-to-EDDM3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Respiratory system development grouped by EDDM3A-low versus EDDM3A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDDM3A→partner) and Y-score (partner→EDDM3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Respiratory system development →	+0.042	+0.086	<.001	<.001	3	11
ESCA	Positive regulation of immune effector process →	+0.056	+0.142	<.001	<.001	3	11
ESCA	B cell activation →	+0.043	+0.091	<.001	.001	3	11
STAD	Regulation of calcium ion export across plasma membrane →	+0.038	+0.101	<.001	<.001	3	10
ESCA	Negative regulation of cysteine-type endopeptidase activity →	+0.060	+0.106	<.001	<.001	3	10
STAD	Regulation of small GTPase mediated signal transduction →	+0.045	+0.095	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,799 associations by consensus.

Respiratory system development by EDDM3A expression — STAD

Explore this box plot interactively →