EDA

Across TCGA patient cohorts, EDA RNA expression is significantly associated with the protein abundance of many other proteins, with 9,654 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EDA-associated proteins across cancer lineages are MIOS_S766, COIL_T303, and STAT1. Each is linked with EDA in more than 3 cancer types. Because this analysis shows association rather than direction, both EDA-to-partner and partner-to-EDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EDA versus MIOS_S766 in OV, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EDA→partner) and Y-score (partner→EDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MIOS_S766 →	-0.613	-0.580	<.001	.001	3	4
OV	COIL_T303 →	-0.850	-0.530	<.001	<.001	3	4
CCRCC	STAT1 →	-0.732	-0.759	<.001	<.001	3	4
CCRCC	PARP14 →	-0.381	-0.699	<.001	<.001	3	3
GBM	PAWR →	+0.643	+0.456	<.001	<.001	3	3
PDAC	ACAP1 →	-0.334	-0.263	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,654 associations by consensus.

EDA vs MIOS_S766 — OV

Explore this scatter interactively →