ECSCR

Across TCGA cell cohorts, ECSCR RNA expression is significantly associated with the go_rna of many other GO terms, with 2,547 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ECSCR-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Dentinogenesis, and Skeletal muscle fiber development. Each is linked with ECSCR in more than 7 cancer types. Because this analysis shows association rather than direction, both ECSCR-to-partner and partner-to-ECSCR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by ECSCR-low versus ECSCR-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECSCR→partner) and Y-score (partner→ECSCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	+0.228	+0.604	<.001	.002	3	8
OVARY	Dentinogenesis →	+1.207	+1.924	<.001	<.001	3	7
LIVER	Skeletal muscle fiber development →	+0.154	+0.620	.005	.004	3	7
BLOOD_Lymphoma	Establishment or maintenance of microtubule cytoskeleton polarity →	+0.149	+0.344	<.001	<.001	3	6
LIVER	Nuclear body organization →	+0.110	+0.750	.001	.002	3	6
OVARY	Positive regulation of glutamate secretion, neurotransmission →	+0.123	+2.375	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,547 associations by consensus.

Establishment of epithelial cell apical/basal polarity by ECSCR expression — URINARY_TRACT

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