Across TCGA patient cohorts, ECI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,345 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ECI2-associated proteins across cancer lineages are MBNL2, NFIA, and UPP1. Each is linked with ECI2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ECI2-to-partner and partner-to-ECI2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI2→partner) and Y-score (partner→ECI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MBNL2 →	-0.412	-0.744	.003	.008	3	4
BRCA	NFIA →	+0.459	+0.671	<.001	<.001	3	4
UCEC	UPP1 →	-0.579	-0.698	<.001	.002	3	4
OV	WRNIP1 →	+0.582	+0.683	<.001	<.001	3	4
UCEC	GMDS →	+0.543	+0.829	<.001	<.001	3	4
UCEC	HOOK2 →	+0.241	+0.986	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,345 associations by consensus.

Exploration

ECI2 survival (RNA) · tumor vs normal (RNA) · all ECI2 data types