ECI1

Across TCGA patient cohorts, ECI1 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ECI1-associated genes across cancer lineages are MTND5P7, MIR101-2, and SNORA1B. Each is linked with ECI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ECI1-to-partner and partner-to-ECI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND5P7 grouped by ECI1-low versus ECI1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI1→partner) and Y-score (partner→ECI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTND5P7 →	+0.015	+4.144	<.001	.009	3	2
COAD	MIR101-2 →	+0.569	+3.542	<.001	.005	3	2
COAD	SNORA1B →	+0.494	+3.542	.002	.005	3	2
COAD	MIR138-1 →	+0.272	+5.412	<.001	.001	3	2
COAD	RN7SL617P →	+0.425	+3.602	<.001	.005	3	2
SKCM	RPL5P16 →	+0.048	+5.436	.009	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

MTND5P7 by ECI1 expression — CESC

Explore this box plot interactively →