ECI1

Across TCGA pan-cancer cohorts, ECI1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ECI1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where ECI1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ECI1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

UCEC, BRCA, and LIHC are the cancer types where ECI1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ECI1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	III,IV	+0.891	<.001	6	view →
BRCA	All	III,IV	+0.685	<.001	6	view →
LIHC	Female	All	+0.491	<.001	6	view →
KIRP	All	II,III,IV	+0.517	.003	4	view →
THCA	Male	III,IV	−0.638	.011	3	view →
LUSC	All	All	+0.269	.008	3	view →
LUAD	All	IV	+1.210	.031	2	view →
STAD	All	II,III,IV	+0.411	.012	2	view →
COAD	Female	All	+0.402	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ECI1–UCEC

Open the UCEC breakdown →