ECI1

Across TCGA patient cohorts, ECI1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ECI1-associated genes across cancer lineages are CD8+ T-cells, MPP, and CD8+ Tcm. Each is linked with ECI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ECI1-to-partner and partner-to-ECI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by ECI1-low versus ECI1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI1→partner) and Y-score (partner→ECI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.054	+3.430	<.001	.007	3	2
COAD	MPP →	+0.016	+4.403	.042	<.001	3	2
UCEC	CD8+ Tcm →	+0.084	+3.520	<.001	.006	3	2
UCEC	CD4+ naive T-cells →	+0.007	+3.530	.042	.020	3	2
LUSC	Chondrocytes →	+0.020	+4.694	<.001	.014	3	1
COAD	GMP →	+0.100	+2.884	<.001	.012	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CD8+ T-cells by ECI1 expression — UCEC

Explore this box plot interactively →