ECI1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ECI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,786 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ECI1-associated GO terms across cancer lineages are Alditol biosynthetic process, Glycerol biosynthetic process, and Endodermal cell differentiation. Each is linked with ECI1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ECI1-to-partner and partner-to-ECI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alditol biosynthetic process grouped by ECI1-low versus ECI1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI1→partner) and Y-score (partner→ECI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEAlditol biosynthetic process →+0.150+0.996.001<.001311
SOFT_TISSUEGlycerol biosynthetic process →+0.150+0.996.001<.001311
BREASTEndodermal cell differentiation →-0.144-0.489.004.00439
UPPER_AERODIGESTIVE_TRACTRegulation of collagen biosynthetic process →-0.101-0.862.002.00139
LUNG_NSCLC_LUADRegulation of wound healing →-0.069-0.849.004.00139
BONECalcium-independent cell-matrix adhesion →+0.217+2.122<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,786 associations by consensus.

Alditol biosynthetic process by ECI1 expression — SOFT_TISSUE

Box plot of Alditol biosynthetic process in ECI1-low vs ECI1-high samples in SOFT_TISSUE.

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Exploration