ECHDC3

Across TCGA patient cohorts, ECHDC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,462 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ECHDC3-associated proteins across cancer lineages are SIPA1_S839, UCK1_S253, and PHYH. Each is linked with ECHDC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ECHDC3-to-partner and partner-to-ECHDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECHDC3 versus SIPA1_S839 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC3→partner) and Y-score (partner→ECHDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIPA1_S839 →	+0.475	+0.844	.001	<.001	3	3
LUAD	UCK1_S253 →	+0.326	+0.676	.004	.001	3	3
BRCA	PHYH →	+0.555	+0.722	<.001	<.001	3	3
CCRCC	RBP7 →	+0.618	+0.683	<.001	<.001	3	3
CCRCC	OPLAH_S419 →	+0.625	+1.032	<.001	.004	3	3
CCRCC	PARD6B_S259 →	+0.728	+0.741	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,462 associations by consensus.

ECHDC3 vs SIPA1_S839 — GBM

Explore this scatter interactively →