ECHDC3

Across TCGA patient cohorts, ECHDC3 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ECHDC3-associated genes across cancer lineages are RNU4ATAC15P, RN7SKP247, and SIM1-AS1. Each is linked with ECHDC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ECHDC3-to-partner and partner-to-ECHDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4ATAC15P grouped by ECHDC3-low versus ECHDC3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC3→partner) and Y-score (partner→ECHDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU4ATAC15P →	+0.576	+5.685	<.001	.003	3	2
BLCA	RN7SKP247 →	+0.194	+4.973	<.001	.009	3	1
BLCA	SIM1-AS1 →	+0.153	+5.788	.006	.003	3	1
BLCA	OR10G9 →	+0.054	+7.040	<.001	<.001	3	1
BLCA	RN7SL340P →	+0.283	+5.251	<.001	.006	3	1
BLCA	RPL38P1 →	+0.205	+5.411	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

RNU4ATAC15P by ECHDC3 expression — BLCA

Explore this box plot interactively →