ECHDC1

Across TCGA cell cohorts, ECHDC1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ECHDC1-associated genes across cancer lineages are LGALS13, PRSS54, and C14orf180. Each is linked with ECHDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ECHDC1-to-partner and partner-to-ECHDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS13 grouped by ECHDC1-low versus ECHDC1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC1→partner) and Y-score (partner→ECHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	LGALS13 →	+0.466	+5.807	<.001	.001	3	1
LARGE_INTESTINE	PRSS54 →	+0.046	+3.930	<.001	.003	3	1
LARGE_INTESTINE	C14orf180 →	+0.126	+4.155	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LGALS13 by ECHDC1 expression — OVARY

Explore this box plot interactively →