ECH1

Across TCGA cell cohorts, ECH1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,017 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ECH1-associated genes across cancer lineages are COQ8B, SIRT2, and U2AF1L4. Each is linked with ECH1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ECH1-to-partner and partner-to-ECH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECH1 versus COQ8B in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.67.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECH1→partner) and Y-score (partner→ECH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	COQ8B →	+1.352	+1.200	<.001	<.001	3	11
LUNG_NSCLC_LUAD	SIRT2 →	+0.974	+0.952	<.001	<.001	3	11
OESOPHAGUS	U2AF1L4 →	+1.294	+1.764	.001	.002	2	10
UPPER_AERODIGESTIVE_TRACT	FAM98C →	+0.929	+1.291	<.001	<.001	2	10
BLOOD_Leukemia	YIF1B →	+1.044	+0.684	<.001	<.001	3	9
OESOPHAGUS	MED29 →	+1.043	+1.628	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,017 associations by consensus.

ECH1 vs COQ8B — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →