ECEL1

Across TCGA cell cohorts, ECEL1 mutation is significantly associated with the mutation status of many other genes, with 3,390 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ECEL1-associated genes across cancer lineages are CARD11, ERF, and KDM3B. Each is linked with ECEL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ECEL1-to-partner and partner-to-ECEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CARD11 grouped by ECEL1-low versus ECEL1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECEL1→partner) and Y-score (partner→ECEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CARD11 →	+2.655	+4.113	.009	.009	1	5
LUNG_NSCLC_LUAD	ERF →	+4.772	+5.339	.004	.004	1	4
LUNG_NSCLC_LUAD	KDM3B →	+5.772	+5.772	.002	.002	1	4
SOFT_TISSUE	GRIN2A →	+4.502	+5.066	.007	.007	1	4
LARGE_INTESTINE	GOLGA6L2 →	+2.409	+2.767	.001	.001	1	4
LARGE_INTESTINE	THBD →	+3.439	+3.693	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,390 associations by consensus.

CARD11 by ECEL1 expression — SKIN

Explore this box plot interactively →