ECE1

Across TCGA patient cohorts, ECE1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,510 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ECE1-associated genes across cancer lineages are DCAF8, SETDB1, and RPRD2. Each is linked with ECE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ECE1-to-partner and partner-to-ECE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECE1 versus DCAF8 in LSCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECE1→partner) and Y-score (partner→ECE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DCAF8 →	-0.484	-0.494	<.001	<.001	3	5
LSCC	SETDB1 →	-0.421	-0.481	<.001	<.001	3	5
COAD	RPRD2 →	-0.655	-0.241	<.001	<.001	3	5
UCEC	ECE1-AS1 →	+0.784	+0.513	<.001	<.001	3	5
UCEC	NTPCR →	-0.600	-0.455	<.001	<.001	3	4
GBM	SLC16A3 →	+0.853	+0.387	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,510 associations by consensus.

ECE1 vs DCAF8 — LSCC

Explore this scatter interactively →