ECE1-AS1

Across TCGA pan-cancer cohorts, ECE1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ECE1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ECE1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ECE1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

KIRC, UVM, and KIRP are the cancer types where ECE1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.551	0.691	<.001	151	view →
UVM	DFS	Median	All	0.313	0.602	<.001	127	view →
KIRP	OS	Median	II,III,IV	0.322	0.877	.002	82	view →
BRCA	OS	Tertile	II,III,IV	0.947	0.879	.001	75	view →
HNSC	DFS	Tertile	IV	0.758	0.562	.002	72	view →
ACC	OS	Tertile	II,III,IV	0.391	0.869	<.001	71	view →
MESO	OS	Tertile	II,III,IV	0.269	0.577	<.001	52	view →
LGG	DFS	Median	All	0.662	0.812	<.001	50	view →
SKCM	OS	Tertile	All	0.422	0.238	<.001	38	view →
READ	DFS	Quartile	IV	0.314	0.806	.004	9	view →
STAD	OS	Median	IV	0.705	0.159	.011	9	view →
PRAD	DFS	Quartile	All	0.711	0.863	.019	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ECE1-AS1–KIRC (OS)

Open the KIRC breakdown →