ECE1-AS1

Across TCGA pan-cancer cohorts, ECE1-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ECE1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ECE1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ECE1-AS1 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

LUAD, HNSC, and KIRC are the cancer types where ECE1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ECE1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.399	<.001	7	view →
HNSC	Male	All	+0.172	.003	7	view →
KIRC	Male	All	+0.115	<.001	7	view →
COAD	All	II,III,IV	−0.098	.023	3	view →
CHOL	All	All	+0.271	.001	2	view →
LUSC	Male	All	+0.221	.007	2	view →
BRCA	All	III,IV	−0.174	.009	2	view →
THCA	All	III,IV	+0.240	.028	1	view →
KIRC	Female	IV	−0.119	.034	1	view →
KICH	All	All	−0.117	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 9 lineages.

ECE1-AS1–LUAD

Open the LUAD breakdown →