EBPL

Across TCGA patient cohorts, EBPL mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible EBPL-associated genes across cancer lineages are RNU6-591P, RRAGAP1, and RNU6-792P. Each is linked with EBPL in more than 1 cancer types. Because this analysis shows association rather than direction, both EBPL-to-partner and partner-to-EBPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by EBPL-low versus EBPL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBPL→partner) and Y-score (partner→EBPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-591P →	+0.358	+7.741	<.001	.009	3	2
UCEC	RRAGAP1 →	+0.170	+3.409	.002	.003	3	2
UCEC	RNU6-792P →	+0.245	+4.400	.004	.006	3	1
UCEC	RNA5SP204 →	+0.586	+3.303	<.001	.004	3	1
COAD	RNU6-1167P →	+0.392	+7.741	<.001	.009	3	1
COAD	MIR548F5 →	+0.412	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

RNU6-591P by EBPL expression — COAD

Explore this box plot interactively →