EBPL

Across TCGA pan-cancer cohorts, EBPL RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of EBPL’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where EBPL RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EBPL is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, KIRC, and STAD are the cancer types where EBPL tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EBPL RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.293	<.001	11	view →
KIRC	Male	All	+0.819	<.001	11	view →
STAD	All	II,III,IV	+0.830	<.001	8	view →
BLCA	Male	All	+0.823	.005	7	view →
KIRP	All	II,III,IV	+0.577	.003	6	view →
READ	All	All	+1.078	<.001	5	view →
HNSC	Male	All	+0.500	.011	5	view →
BRCA	All	All	+0.232	.012	4	view →
THCA	Male	All	−0.384	.003	3	view →
KICH	Female	All	−0.862	.003	2	view →
LIHC	Female	All	−0.697	.001	2	view →
LUSC	All	All	+0.295	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

EBPL–COAD

Open the COAD breakdown →