EBPL

Across TCGA cell cohorts, EBPL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,612 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EBPL-associated GO terms across cancer lineages are Sister chromatid biorientation, D-ribose metabolic process, and Mitochondrial gene expression. Each is linked with EBPL in more than 10 cancer types. Because this analysis shows association rather than direction, both EBPL-to-partner and partner-to-EBPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid biorientation grouped by EBPL-low versus EBPL-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EBPL→partner) and Y-score (partner→EBPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Sister chromatid biorientation →	+0.173	+0.891	<.001	.002	3	11
OESOPHAGUS	D-ribose metabolic process →	+0.229	+0.752	.002	.001	3	10
CNS	Mitochondrial gene expression →	+0.084	+1.122	<.001	<.001	3	9
LUNG_SCLC	Mitochondrial translation →	+0.121	+0.954	<.001	<.001	3	9
BONE	Malate metabolic process →	+0.124	+0.757	.001	.005	3	9
LARGE_INTESTINE	Regulation of protein deubiquitination →	-0.101	-0.645	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,612 associations by consensus.

Sister chromatid biorientation by EBPL expression — BONE

Explore this box plot interactively →