EBI3

Across TCGA patient cohorts, EBI3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible EBI3-associated genes across cancer lineages are CD4+ Tcm and CMP. Each is linked with EBI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBI3-to-partner and partner-to-EBI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by EBI3-low versus EBI3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBI3→partner) and Y-score (partner→EBI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD4+ Tcm →	+0.056	+5.481	<.001	.005	3	2
LUSC	CMP →	+0.027	+3.730	.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tcm by EBI3 expression — LUAD

Explore this box plot interactively →