EAPP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EAPP RNA expression is significantly associated with the protein abundance of many other proteins, with 16,670 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EAPP-associated proteins across cancer lineages are FKBP3, ARHGAP5, and PPP2R5E. Each is linked with EAPP in more than 8 cancer types. Because this analysis shows association rather than direction, both EAPP-to-partner and partner-to-EAPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EAPP versus FKBP3 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EAPP→partner) and Y-score (partner→EAPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVFKBP3 →+0.440+0.481<.001<.00129
HNSCARHGAP5 →+0.326+0.821<.001.00137
PDACPPP2R5E →+0.281+0.199.004.00437
GBMMTHFD1 →+0.279+0.267<.001<.00136
HNSCBAG5 →+0.275+0.691<.001.00136
GBMPPP4R3A →+0.354+0.338<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,670 associations by consensus.

EAPP vs FKBP3 — OV

Per-sample scatter of EAPP vs FKBP3 in OV (Pearson r = 0.35).

Explore this scatter interactively →

Exploration