EAPP

Across TCGA patient cohorts, EAPP protein abundance is significantly associated with the RNA expression of many other genes, with 9,645 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EAPP-associated genes across cancer lineages are FKBP3, AP4S1, and FANCM. Each is linked with EAPP in more than 5 cancer types. Because this analysis shows association rather than direction, both EAPP-to-partner and partner-to-EAPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EAPP versus FKBP3 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EAPP→partner) and Y-score (partner→EAPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FKBP3 →	+0.583	+0.381	<.001	<.001	3	6
OV	AP4S1 →	+0.531	+0.459	.001	<.001	2	6
COAD	FANCM →	+0.529	+0.344	.002	.008	3	5
LSCC	ALKBH1 →	+0.289	+0.235	<.001	<.001	3	4
LSCC	VRK1 →	+0.615	+0.225	<.001	<.001	3	4
COAD	NUP88 →	+0.793	+0.468	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,645 associations by consensus.

EAPP vs FKBP3 — LSCC

Explore this scatter interactively →