EAPP

Across TCGA cell cohorts, EAPP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EAPP-associated GO terms across cancer lineages are Vesicle coating, Vesicle targeting, rough ER to cis-Golgi, and Protein catabolic process at synapse. Each is linked with EAPP in more than 12 cancer types. Because this analysis shows association rather than direction, both EAPP-to-partner and partner-to-EAPP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle coating grouped by EAPP-low versus EAPP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EAPP→partner) and Y-score (partner→EAPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Vesicle coating →	+0.085	+0.683	.005	.008	3	13
CNS	Vesicle targeting, rough ER to cis-Golgi →	+0.072	+0.512	.003	.004	3	11
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.172	+0.577	<.001	<.001	3	10
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.172	+0.577	<.001	<.001	3	10
BLOOD_Lymphoma	Vesicle targeting, to, from or within Golgi →	+0.090	+0.856	<.001	<.001	3	10
BREAST	Endosome to lysosome transport →	+0.058	+0.768	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,363 associations by consensus.

Vesicle coating by EAPP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →