EAF2

Across TCGA patient cohorts, EAF2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,490 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EAF2-associated genes across cancer lineages are IFI27L2, CDK4, and RNU6-556P. Each is linked with EAF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EAF2-to-partner and partner-to-EAF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EAF2 versus IFI27L2 in CCRCC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EAF2→partner) and Y-score (partner→EAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IFI27L2 →	-0.687	-1.995	.003	.001	3	2
LSCC	CDK4 →	-0.518	-0.999	.003	<.001	3	2
LSCC	RNU6-556P →	+1.499	+1.218	.004	.002	3	2
LSCC	BRK1 →	-0.442	-1.041	.002	.004	3	2
CCRCC	EIF3D →	-0.405	-1.924	<.001	<.001	3	1
CCRCC	CD40 →	-0.871	-1.692	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,490 associations by consensus.

EAF2 vs IFI27L2 — CCRCC

Explore this scatter interactively →