EAF1

Across TCGA patient cohorts, EAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,393 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EAF1-associated genes across cancer lineages are BUB1, SMC4, and GULP1. Each is linked with EAF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EAF1-to-partner and partner-to-EAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EAF1 versus BUB1 in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EAF1→partner) and Y-score (partner→EAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BUB1 →	+0.863	+0.247	<.001	.002	3	4
BRCA	SMC4 →	+0.696	+0.326	.001	<.001	3	3
UCEC	GULP1 →	-0.746	-0.323	<.001	<.001	3	3
UCEC	IRAG1-AS1 →	-0.867	-0.409	<.001	<.001	3	3
BRCA	MCM10 →	+0.760	+0.216	.003	.008	3	3
BRCA	BIRC5 →	+0.930	+0.284	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,393 associations by consensus.

EAF1 vs BUB1 — GBM

Explore this scatter interactively →