EAF1-AS1

Across TCGA pan-cancer cohorts, EAF1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated EAF1-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EAF1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated EAF1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, KICH, and BLCA are the cancer types where EAF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.767	0.572	<.001	74	view →
KICH	DFS	Tertile	III,IV	0.222	0.931	.001	69	view →
BLCA	OS	Tertile	II,III,IV	0.499	0.306	.003	67	view →
KIRC	DFS	Tertile	All	0.489	0.717	<.001	48	view →
LUSC	DFS	Median	III,IV	0.225	0.802	.003	45	view →
SKCM	DFS	Quartile	All	0.734	0.533	<.001	35	view →
LGG	DFS	Tertile	All	0.752	0.873	<.001	28	view →
UCS	DFS	Tertile	IV	0.936	0.298	.024	24	view →
THCA	OS	Tertile	II,III,IV	0.965	1.000	.005	21	view →
COAD	OS	Tertile	II,III,IV	0.922	0.739	.007	18	view →
THYM	DFS	Tertile	All	1.000	0.652	.009	17	view →
DLBC	DFS	Median	All	0.611	0.929	.006	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

EAF1-AS1–HNSC (DFS)

Open the HNSC breakdown →